An Overview on H2FPEF Score

Abstract

Heart failure with preserved ejection fraction (HFpEF) is a common and complex clinical syndrome characterized by signs and symptoms of heart failure despite a normal or near-normal left ventricular ejection fraction (LVEF ≥50%). Diagnosing HFpEF can be particularly challenging, as patients often present with non-specific symptoms such as exertional dyspnea, and traditional heart failure diagnostics may not definitively confirm the condition. To address this diagnostic uncertainty, the H2FPEF Score was developed by Dr. Barry A. Borlaug and colleagues at the Mayo Clinic and published in Circulation in 2018. The score provides a simple, evidence-based tool to estimate the likelihood that a patient's symptoms are due to HFpEF rather than non-cardiac or alternative cardiovascular causes.